Projects
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Four ppt lecture files that are part of a UvA course on 'How to design an alien'. They correspond to four lectures given by Hans V. Westerhoff, September - October 2021
Programme: ISBE.NL service programme
Public web page: Not specified
The Hippo signalling is a metabolic control pathway of cells proliferation and apoptosis, thus represents an emerging topic in tumour suppression regulation and regenerative medicine. This pathway is activated by anti-proliferative signals which come from the extracellular environment received by membranes proteins. In the cytosol compartment, the pathway is regulated by a phosphorylation cascade of four main proteins with Serin-Treonin kinase activity. At the end-point of this cascade the ...
Programme: Cancer drug discovery preclinical research
Public web page: Not specified
Testing stuff
Programme: Data_Management_lessons
Public web page: Not specified
Programme: Independent Projects
Public web page: Not specified
testing project to evaluate capabilities of SEEK
Programme: Multicomponent Therapy for Age-related Skin Stem Cell Deficiency
Public web page: Not specified
Just a test
Programme: Independent Projects
Public web page: Not specified
A project created for demonstration
Programme: This Project is not associated with a Programme
Public web page: Not specified
Test project to see Fairdom capabilities.
Programme: Test program
Public web page: Not specified
Assessing different tools for RDM
Programme: MPIB
Public web page: Not specified
Programme: Independent Projects
Public web page: Not specified
to test the api
Programme: Independent Projects
Public web page: Not specified
Programme: Independent Projects
Public web page: Not specified
Programme: Systems Brewology
Public web page: Not specified
The placenta remains the key to maternal diseases such as Pre-eclampsia (PE) and Intrauterine growth restriction (IUGR), however the pathophysiology of these disorders remains elusive. The aim of this study is to characterize the key proteomic variations between PE and IUGR, to better understand the pathoetiology of these diseases.Term placentas each were collected from PE, IUGR pregnancies, and age and BMI matched healthy controls. Quadrupole-orbitrap mass spectrometer was used in data dependent ...
Programme: iPlacenta: A European Union Horizon 2020 innovative training network (ITN)
Public web page: Not specified
To systematically evaluate the general efficacy of nape acupuncture combined with rehabilitation training for the treatment of post-stroke dysphagia and in the recovery of swallowing function.
Programme: The Effect of Nape Acupuncture Combined with Rehabilitation Training on Dysphagia After Stroke
Public web page: Not specified
This project stored supplementary files that we didn't include in the paper ' Exploring the Evolution of the Gene Ontology and itsImpact on Enrichment Analysis'
Programme: Hallmarks of cancer
Public web page: Not specified
Programme: LiSyM - Systems Medicine of the Liver
Public web page: Not specified
Programme: Independent Projects
Public web page: Not specified
the Supplementary materials for Journal of Clinical Endocrinology and Metabolism
Programme: Independent Projects
Public web page: Not specified
A chapter on generalized thermodynamics. The chapter is not specifically about biology although it uses many examples in biology due to the richness of the topic. It deals with the first and second law of thermodynamics, catalysts, and engines. This includes heat engines, heat pumps, and protonmotive ATP synthase.
Programme: Thermodynamics and kinetics for Biology
Public web page: http://sysba.nl/
Start date: 8th Apr 2021
End date: 8th Apr 2031
Programme: Thesis AHG 2019
Public web page: Not specified
Designing 3D metamaterials
Programme: 3DMM2O
Public web page: https://www.3dmattermadetoorder.kit.edu/metamaterials.php
Programme: Cancer drug discovery preclinical research
Public web page: Not specified
EU FP7 collaborative project TiMet, award number 245143. Funded 2010-2015. "TiMet assembles world leaders in experimental and theoretical plant systems biology to advance understanding of the regulatory interactions between the circadian clock and plant metabolism, and their emergent effects on whole-plant growth and productivity."
Programme: SynthSys
Public web page: http://timing-metabolism.eu/
generation of a toggle switch based on a non-cooperative network
Programme: Von Hippel-Lindau (VHL) Tumor Suppressor research programme
Public web page: Not specified
Start date: 2nd Jan 2020
End date: 1st Apr 2025
Investigation 1: An experimental workflow to provide detailed information of the molecular mechanisms of enzymes is described. This workflow will help in the application of enzymes in technical processes by providing crucial parameters needed to plan, model and implement biocatalytic processes more efficiently. These parameters are homogeneity of the enzyme sample (HES), kinetic and thermodynamic parameters of enzyme kinetics and binding of reactants to enzymes. The techniques used to measure ...
A fundamental and enduring challenge for ecosystem managers developing risk and impact assessment tools is to predict the extent of impact that spilled oil can have on the immediate fish populations and on future generations. Modelling approaches are important tools for these assessments, but they currently suffer from two major shortcomings: 1) the failure to acknowledge that effects can be transferred through several generations and 2) the assumption that a small group of toxic compounds, ...
Programme: Independent Projects
Public web page: https://uit.no/project/toxigen
Start date: 17th Sep 2023
End date: 31st Dec 2027
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
Amino alcohol moieties are found in highly diverse classes of natural products that are of great importance due to their bioactivity, and they function as chiral building blocks for the synthesis of pharmaceuticals and agrochemicals. The chemical synthesis of stereoisomerically pure amino alcohols is difficult and typically requires uneconomical steps for protective group manipulations. Conventional syntheses in the chemical industry often use hazardous substances, consume large amounts of energy ...
Programme: Era CoBioTech
Public web page: https://www.cobiotech.eu/call-information
Start date: 1st Apr 2018
End date: 31st Mar 2021
Programme: e:med
Public web page: https://kohlbacherlab.org
Gene interaction networks and models of cation homeostasis in Saccharomyces cerevisiae
Programme: SysMO
Public web page: http://www.translucent-network.org/