Projects

Further proteomic data and ATP calculation

Development of a lactic acid centred biorefinery scheme to valorize flexibly organic waste streams into biochemicals

Testing out FAIRDOM-Seek

Cyanobacteria are the only prokaryotes performing oxygenic photosynthesis. Theyhad and have tremendous influence on the biogeochemical cycles on Earth. Recently,cyanobacteria are increasingly investigated as cell factories for a sustainableeconomy. Despite their global, environmental and rising economic importance, ourknowledge on the regulation of their primary metabolism is fragmented.Cyanobacteria switch between photoautotrophic and heterotrophic modes ofmetabolism during day/night cycles or ...

MESI-Review 2024

The group around Nicole Radde specializes in the modeling, analysis, and simulation of biochemical systems. This especially includes parameter optimization and identification.

MESI-STRAT: Systems Medicine of Metabolic-Signaling Networks -A New Concept for Breast Cancer Patient Stratification. Breast cancer is a complex disease with high prevalence in the European Union and world-wide. 75%-80 of the patients have estrogen receptor-positive (ER)-positive tumors and are treated with endocrine therapies. Endocrine therapies, which block ER-driven tumor growth, show high efficacy. Yet, a significant proportion of the patients will eventually relapse with metastatic breast ...

Cell biological and proteogenomic study of the chloroplast of the marine, bloom-forming dinoflagellate P. cordatum

This data contains fish data such as fish abundance, fish community structure data, fish species data obtained in the study, fish productivity and also fish length-weight relationships.

This research discusses what is the status of fisheries provisioning services in Jatigede Reservoir and what anthropogenic pressures in the form of community activities affect the status of fisheries provisioning services.

MESI-STRAT Review

-engineering next level photosynthesis-PhotoBoost is a 4-year research and innovation action that aims to significantly improve the efficiency of photosynthesis in plants. The optimisation of photosynthesis will be achieved by capitalising on multidisciplinary approaches including computational biology, metabolic modelling, systems biology, enzyme and pathway engineering, synthetic biology, and the multigene transformation of two major C3 crops: potato and rice. The PhotoBoost project will deliver ...

This project aims to streamline the integration of Japanese plant research data into the global data ecosystem using the FAIR Data-finder for Agronomic Research (FAIDARE) and Breeding API (BrAPI) standards. Despite the large and diverse datasets generated in plant research, there are significant barriers to efficient data use due to findability and interoperability issues. Our initiative addresses these challenges by adopting the Minimum Information About Plant Phenotyping Experiments (MIAPPE) ...

A fundamental and enduring challenge for ecosystem managers developing risk and impact assessment tools is to predict the extent of impact that spilled oil can have on the immediate fish populations and on future generations. Modelling approaches are important tools for these assessments, but they currently suffer from two major shortcomings: 1) the failure to acknowledge that effects can be transferred through several generations and 2) the assumption that a small group of toxic compounds, ...

PoLiMeR is funded through the EU Marie Skłodowska-Curie Innovative Training Network (ITN), which drives scientific excellence and innovation. ITNs bring together universities, research institutes, industry and clinical partners from across the world to train researchers to doctorate level.

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease ...

The mission of the Virtual Human Platform is to improve the prediction of the potential harmful effects of chemicals and pharmaceuticals based on a holistic, interdisciplinary definition of human health by developing the Virtual Human Platform and accelerating the transition from animal-based testing to innovative safety assessment. The Virtual Human Platform integrates data on human physiology, chemical characteristics and perturbations of biological pathways, for the first time in an inclusive ...

The current project is created as a potential repository for resources resulting from the Virtual Human Platform for Safety Assessment (VHP4Safety) project.

the Supplementary materials for Journal of Clinical Endocrinology and Metabolism

Independent Project

The main objective of SynBio4Flav is to go further in the standardization of high complexity synthetic biological parts, and to demonstrate the development of a standardized, and systematic platform for flavonoids production based on synthetic microbial consortia (SMCs).

Test case for porting sampleBD to fairdom-seek