Programmes
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Projects: WP 1: Biodegradable and responsive polymer matrix, WP 2: Antimalarial drug encapsulation, WP 3: Drug release kinetics study, WP 4: Evaluation of drug activity against multiple life cycle stages of malaria parasites, WP 5: Intradermal 3D drug device administration, Project Coordination
Web page: Not specified
We develop macrophage logical models to represent the activation/polarization of this immune cell. Interactions are manually curated with available macrophage literature. The models are mainly built and analyzed in GINsim. But other resources are used to integrate specific pathways or small modules (CasQ software) and to analyze the logical models (CoLoMoTo Notebooks).
Projects: C19DM - Macrophage logical model
Web page: Not specified
Projects: Mathematical modelling of the antibiotic-induced morphological transition of Pseudomonas aeruginosa
Web page: Not specified
ISBE-Light provides M4 service (Make Me My Mode) where non modelers can request (assistance with) the making of a computational model of their biological system. These models are deposited here.
Projects: Service to Milano-Bicocca with respect to their ATP-ROS model (Active NOW), Service to University of Lisbon (Portugal) with respect to their CFTR maturation model (Active NOW), Service to LCSB (Luxembourg) with respect to ROS management in Parkinson’s disease and cancer model (Active NOW), Service to URV Tarragona, Spain with respect to their Safety Assessment of Endocrine Disrupting Chemicals model (Active NOW), Service to Universidade Católica Portugues with respect to their Molecular Insight into Autism Spectrum Disorder (ASD) model (Active NOW), Service to Slovenia with respect to their Protease signaling network in neurodegeneration model (Active NOW), Service to University of Duisburg- Essen (Germany): with respect to their The Yin-Yang of Metabolism; Endometatoxicity (YYME) model (Active NOW), Service to Sheffield University (UK): with respect to Mitochondrial perfect adaptation model (Active NOW), Service to Sanquin (Amsterdam): with respect to Modelling of acute and chronic inflammation (Prospective), Service to Munich (Germany): with respect toCharged peptide to charged membrane binding model (Prospective), Training Hunfeld, EraCoBiotech 2 nd call proposal preparation, ROS detailed model for MSB manucript, Mechanism based modeling viral disease ( COVID-19 ) dynamics in human population
Web page: http://www.isbe.nl
Plant development is strongly influenced by external light cues, yet we know very little of how this is mediated at a molecular level. This BBSRC funded project seeks to determine how phytochrome light receptor signalling connects with the developmental pathways to control plant architecture.
Projects: Light and plant development
Web page: http://hallidaylab.bio.ed.ac.uk
Projects: Testing tools for research data management
Web page: Not specified